2nd Expert Workshop on the development of tests for progression of latent tuberculosis infection (LTBI) to active disease
On 1st July 2016, the NDWG convened an expert workshop on LTBI hosted by San Raffaele Scientific Institute in Milan, Italy. The objectives of the meeting were as follows:
- To propose a standard terminology for LTBI and LTBI diagnostics.
- To finalize the TPP for a test of progression and define a dissemination strategy for the document
- To prepare an advanced draft of a guidance document for the evaluate of such a test and eventually submit it for WHO approval.
- To provide an overview of the most promising research in this area.
Presentations:
Introduction and objectives of the meeting - Alberto Matteelli
LTBI conception: Definitions and relevance for diagnostic products - Frank Cobelens
Preliminary results of the online consultation on the draft TPP - Susanna Capone
TTP for a test of progression: Key areas to be addressed based on survey results - Samuel Schumacher
Framework for the evaluation of new LTBI tests - Sandra Kik
Genomic signatures - Thomas Scriba
Role of CD8 in progression from latent to active TB - David Lewinsohn