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Organization Contact Information

Name: Liverpool School of Tropical Medicine
Street 1: Pembroke Place
Street 2:
City: Liverpool
Province:
Post Code: L35QA
Country: United Kingdom of Great Britain and Northern Ireland
Phone: +44(0)151 705 3100
Organization Email: info@lstmed.ac.uk
Web Site: http://www.lstmed.ac.uk
Other Online Presence:

Focal Point Contact Information

Salutation: Dr
First Name: Kerry
Last Name: Millington
Title: Research Uptake Manager
Email: kerry.millington@lstmed.ac.uk
Phone:  

Alternate Focal Point Contact Information

Salutation: Dr
First Name: Tom
Last Name: Wingfield
Title: Reader in Tuberculosis and Social Medicine & Honorary Consultant Physician in Infectious Diseases & GIM
Email: tom.wingfield@lstmed.ac.uk
Phone:  

General Information

Board Constituency: None
Is your organization legally registered in your country: Yes
If yes, please enter your registration number: 00083405
Organization Type - Primary: Academic / Research Institution
Organization Type - Secondary: None
Organization Description:
The Liverpool School of Tropical Medicine (LSTM) is the first institution dedicated to research and teaching in the field of tropical medicine and will be celebrating 125 years of global health impact in 2023. LSTM’s vision is for healthy lives across the world through improving health outcomes in disadvantaged populations globally, through partnership in research and education.

The School’s work in combating diseases such as TB, HIV/AIDS, malaria, dengue and lymphatic filariasis is supported by a research portfolio of over £210 million and is at the forefront of infectious disease research. Attracting over 600 students from 68 countries, the School works in partnership with health ministries, universities, and research institutions worldwide to train the next generation of doctors, scientists, researchers and health professionals.

Ending TB remains at the heart of our mission to improve health outcomes in disadvantaged populations globally. Our collaborative education, research, and knowledge exchange helps us reach more people with TB, making the global TB response more equitable, inclusive, gender-sensitive, and people-centred.
 
Do you know about the UNHLM declaration: Yes

Specializations / Areas of Work

Advocacy
Civil Society and Community Engagement
Research and Development
Working on Community, Rights and Gender (CRG)
Working on Key Populations related to TB

Other Organization Information

Total number of staff in your organization: 100 +
Number of full-time staff who are directly involved with TB: 26 - 50
Number of part-time staff who are directly involved with TB: 26 - 50
Number of volunteers who are directly involved with TB: 0
 
How did you hear about the Stop TB Partnership: Attendance at a TB related event
If you were informed or referred by another partner of the Stop TB Partnership please tell us who:
Why do you wish join the Stop TB Partnership: Involvement in Stop TB Working Groups
 
Are you a member of a Stop TB national partnership: No
Are you in contact with your national TB programme: Yes
Please tell us how your organization is contributing to your country's national TB control plan:
LSTM TB staff are members of the UK Academics and Professionals to end TB network. We primarily campaign, advocate and educate the general public, public servants and politicians to improve UK policies on TB and devote more resources to TB research.
 

Geographical Reach

Which country is your headquarters located in: United Kingdom of Great Britain and Northern Ireland
Which countries do you do operate in:
(This includes countries you are conducting activities in)
Cameroon
Democratic Republic of the Congo
Kenya
Malawi
Mozambique
Nepal
Nigeria
Uganda
United Kingdom of Great Britain and Northern Ireland
Viet Nam

Contribution

Please tell us how your organization will contribute to the Global Plan to Stop TB by briefly describing its involvement in any of the areas of work listed below:

TB Care Delivery:
LSTM collaborates in Liverpool through LIV-TB, globally via the SPARKS network, and with fellow social scientists through SSHIFTB and the Union Working Group on Gender Equity in TB.

At LSTM, TB researchers and healthcare professionals join the UK Academics and Professionals to end TB (UKAPTB) network, which works with policymakers, MPs, the UK’s UN Diplomatic Mission, and the TB Community, to create a coordinated, ambitious ask that contributes to a strong UNHLM on TB Political Declaration.

Research:
The LIGHT research programme, funded with UK aid, works with partners in Africa, and local and global stakeholders. It provides new evidence on the effectiveness of gender-sensitive approaches to health care for people with TB in urban, HIV-prevalent settings. New strategies to improve community-based diagnosis and care for people with TB are vitally important.

The new START 4-All programme, funded by Unitaid,(link is external)(opens in a new tab) will develop and evaluate how to scale-up existing and new TB diagnostic combinations, to improve screening and increase access to testing in community and primary care settings. Our dear friend and colleague, the late Professor Luis Cuevas, started this programme.

In Nepal, the Horizon 2020-funded IMPACT-TB project(link is external)(opens in a new tab), led by Dr Maxine Caws with the Birat Nepal Medical Trust(link is external)(opens in a new tab) (BNMT), has shown that actively finding people with TB, increases TB diagnoses, reducing care-seeking costs of people from underserved communities. Also in Nepal, LSTM’s Dr Tom Wingfield is working with BNMT on the Joint Global Health Trial’s funded ASCOT(link is external)(opens in a new tab) pilot trial to identify and address social determinants and consequences of TB(link is external)(opens in a new tab).

TB is expected to account for 25% of all cases of antibiotic resistant disease, shortly. Professor Bertie Squire, Reader Eve Worrall, and Health Economist, Laura Rosu contributed to an LSTM-led economic evaluation of bedaquiline-containing multidrug resistant TB treatment, through the STREAM(link is external)(opens in a new tab) trial. It showed all-oral 9-month treatment plans worked but weren’t cost-effective for many countries, due to the cost of bedaquiline. LSTM’s Dr Naomi Walker is studying drug resistance patterns in Eastern DRC(link is external)(opens in a new tab), alongside the Catholic University of Bukavu, whilst her RNA (ribonucleic acid) analysis of immune responses, during treatment of HIV-associated TB, is funded by the Director’s Catalyst Award.

LSTM’s Prof. Giancarlo Biagini’s team is investigating the pharmacology and resistance of TB drugs and working on pre-clinical projects to develop new inhibitors, funded by the MRC(link is external)(opens in a new tab) and GCRF(link is external)(opens in a new tab), with national and international academic partners and non-academic partners like TBAlliance(link is external)(opens in a new tab) and pharma. The team is also helping to develop a TB human challenge model to support new therapeutics and vaccine studies.

Elsewhere, The Medical Research Foundation(link is external)(opens in a new tab) recently awarded Dr Tom Wingfield and Dr Celso Khosa(link is external)(opens in a new tab) a Dorothy Temple Cross International TB Collaboration Award to conduct the SAFEST-1 MDR-TB(link is external)(opens in a new tab) study evaluating whether video-observed therapy is suitable for people with drug-resistant TB in Mozambique.

Declaration

Declaration of interests:
No conflicts of interest were delacred.

Application date: August 24, 2023
Last updated: April 1, 2025