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Médicin Sans Frontières

Merieux Alliance

The International Union of TB and Lung Diseases

McGill University

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Institute of Tropical Medicine

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treat TB

Building Global Capacity for Diagnostic Testing of Tuberculosis, Malaria, and HIV Through Laboratory Strengthening and Integration of Services under the President’s Emergency Plan for AIDS Relief (PEPFAR) (CDC-RFA-PS10-10121)

Issuing agency: CDC
Issue date: January 19, 2010
Response date: March 17, 2010
Level of funding: $10 million
Keywords: diagnostic testing, tuberculosis, malaria, HIV, laboratory services, capacity building, integration of services, health systems strengthening

The purpose of this program is to provide technical assistance to build indigenous capacity for:

  • Development of QA practices leading to accreditation of Tuberculosis (TB) laboratories;
  • Integration of services to assure the strengthening of laboratory diagnosis of TB, malaria, HIV, and other opportunistic infections;
  • Implementation of the World Health Organization and Centers for Disease Control and Prevention (WHO/CDC) training materials for TB Acid-fast bacillus (AFB) smear microscopy and External Quality Assessments (EQA) at the District level;
  • Training and mentoring for implementation of TB culture and molecular testing (line-probe assay) using standardized training materials developed together with partners for the African Centre for Integrated Laboratory Training (ACILT);
  • Expansion of in-country TB diagnostics from AFB smear microscopy to liquid culture;
  • In-country validation of new TB and malaria diagnostic procedures; and
  • Development of national integrated laboratory policies and strategic plans.

The complete RFA is available at: here
(Click on "Full Announcement")

Clinical trials, capacity building and networking in new and improved diagnostics for tuberculosis (TB)

Every year on 24 March, the world commemorates World TB Day. The European and Developing Countries Clinical Trials Partnership (EDCTP) wishes to make a contribution to mitigating the effect of this disease by announcing funding opportunities for TB researchers. A call for proposals in TB diagnostics is now open for applications.

Available funds: € 8,000,000*
Number of projects to fund: 2-4
Open to application 24 March 2009
Deadline for application 24 July 2009

* We expect the EDCTP contribution of € 8,000,000 to be matched by at least an equivalent amount of cofunding from the European Member States and possibly further contributions from third parties.

Purpose of the call

The purpose of this call is to develop simpler, cheaper and more accurate TB diagnostic tool(s). The investigational product(s) should be manufactured under Good Manufacturing Practice (GMP). Priority will be given but not limited to products that can be deployed at the Point of Care (POC).

Who can apply?

Participants in a proposal must be drawn from at least two publicly funded institutions from the EDCTP EEIG Member States and at least two sub-Saharan African institutions. Preference will be given to proposals where the project coordinator is a sub-Saharan African national based in Africa. Please note that clinical trials and activities outside of sub-Saharan Africa are outside the scope of EDCTP.

For more details on this call and how to apply, please consult the EDCTP website: www.edctp.org